HPLC/UHPLC Column, Acclaim Mixed-Mode WAX-1

When you need powerful selectivity control for the separation of anionic molecules, use Thermo Scientific™ Acclaim™ Mixed-Mode WAX-1 LC columns. The silica-based stationary phase features a hydrophobic alkyl chain with an ionizable terminus that provides both hydrophobic reversed-phase and weak anion-exchange properties. This unique chemistry produces a multimode separation mechanism for simultaneous separation of acidic, basic, and neutral molecules. The selectivity is fully adjustable through changes to ionic strength, pH, or organic solvent content.

• Multi-mode retention mechanism: reversed-phase, weak anion-exchange, and HILIC modes
• Differentiation of molecules with similar hydrophobicities, such as hydrophilic organic acids
• Selectivity orthogonal to reversed-phase columns
• Excellent column efficiency and peak symmetry
• Stable between pH 2.5 and 7.5
• Available in 3 and 5μm particle sizes with an average pore diameter of 120Å