Base material silica gel, zwitterionic polar phase with ammonium – sulfonic acid modification. Polar analytes are more strongly retained than nonpolar compounds. This behavior is inverse (orthogonal) to RP materials like, e.g., C18 or C8.
| Method | Solid phase extraction (SPE) |
| Brand | CHROMABOND |
| Phase | HILIC |
| Mode | Normal phase (NP) |
| Base material | Silica gel |
| Surface chemistry | Ammonium – sulfonic acid modified silica, zwitterionic, polar |
| Endcapped | No |
| Column type | SPE column |
| Hardware | Polypropylene (PP) columns with polyethylene (PE) filter elements |
| Column shape | Open tubular syringe-shaped column with Luer tip outlet |
| Recommended application(s) | Amino acids, Nucleosides, Oligonucleotides, Peptides, Polar natural compounds, Polar organic acids and bases, Water-soluble vitamins |
| Particle type | Fully porous particles (FPP) |
| Particle size | 45 µm |
| Particle shape | Irregular |
| Specific surface according to BET | 500 m²/g |
| pH stability | 2.0–8.0 |
| Filter element material | Polyethylene (PE) |
| Storage temperature | 15–25 °C / 59–77 °F |
| Scope of delivery | 50x (10×5 in aluminum bags each) SPE columns, certificate of analysis |
| Hazardous material | No |
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