This MaxSignal Fumonisin Immunoaffinity Column can selectively extract Fumonisins (B1, B2, B3) from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after concentrating with nitrogen gas and resuspended.

Fumonisin is a metabolite produced by Fusarium fungi. It has acute and chronic toxicities, and is species-specific and organ-specific. Studies have found that high concentrations of fumonisin can cause acute species-specific toxicity symptoms in many domestic and laboratory animals, such as equine leukoencephalomalacia, porcine pulmonary edema, and liver and kidney diseases in sheep. The toxin has also been found to be related to esophageal and liver cancer in humans.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Fumonisin Immunoaffinity Column can selectively extract Ochratoxin A from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Ochratoxin A is a toxic metabolite produced by some species of Aspergillus and Penicillium; it is a mycotoxin with high kidney and liver toxicities, and has teratogenic, mutagenic, and carcinogenic effects.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal T-2/HT-2 Toxin Immunoaffinity Column can selectively extract T-2 and HT-2 Toxins from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

T-2 toxin (T-2) is a mycotoxin produced by a variety of Fusaria. It mainly pollutes food crops such as wheat, barley, and corn, and their products, and is relatively harmful to human health and cattle industry. HT-2 toxin is the main metabolite of T-2 toxin. These two toxins are strong inhibitors of protein synthesis in the body and mainly affect the functions of blood, liver, kidney, pancreatic muscle and lymphocytes. The general clinical symptoms after poisoning are anorexia, vomiting, diarrhea, growth arrest, as well as reproduction and neurological dysfunction, etc.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Total Aflatoxin Immunoaffinity Column can extract Aflatoxins (B1, B2, G1, G2, M1, M2) from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Aflatoxins are toxic metabolites of a class of fungi (such as Aspergillus flavus and Aspergillus parasiticus). They are highly carcinogenic and are found mainly in grains, peanuts, nuts, cottonseeds, animal feed, vegetable oils, as well as animal tissues and blood. Among them, Aflatoxin B1 ranks first in terms of toxicity, carcinogenicity and frequency of contamination. Aflatoxin M1 is a hydroxylated metabolite of Aflatoxin B1 and a strong carcinogen. Cow milk and its products are prone to Aflatoxin M1 contamination.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Total Aflatoxin Immunoaffinity Column can extract Aflatoxins (B1, B2, G1, G2) from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Aflatoxins are toxic metabolites of a class of fungi (such as Aspergillus flavus and Aspergillus parasiticus). They are highly carcinogenic and are found mainly in grains, peanuts, nuts, cottonseeds, animal feed, vegetable oils, as well as animal tissues and blood. Among them, Aflatoxin B1 ranks first in terms of toxicity, carcinogenicity and frequency of contamination.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Zearalenone Immunoaffinity Column can selectively extract Zearalenone from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Zearalenone (ZEN), also known as F-2 toxin, is mainly produced by Fusarium strains. Its components are 2,4-dihydroxybenzoic acid lactones produced by Fusarium graminearum and Fusarium culmorum. ZEN mainly pollutes crops such as corn, wheat, and grains. It has a strong estrogenic effect and can cause hyperestrogenism, as well as severe reproductive tract symptoms and infertility, and is also immunotoxic and genotoxic.

The basis of the IAC measurement is the antigen-antibody reaction. Antibodies are connected to the column and the toxins in the sample are extracted, filtered, and passed slowly through the zearalenone immunoaffinity column. The toxins bind to the antibodies in the column and the immunoaffinity column is then washed to remove other unrelated substances that have not been bound. Zearalenone is eluted with methanol, and then injected into the analytical instrument for detection.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal 2-in-1 Immunoaffinity Column can simultaneously extract four types of Aflatoxins (B1, B2, G1, G2) and Ochratoxin A (OTA) from various sample types and has a highly targeted purification effect on these two types of toxins. Samples that pass through the column for purification can be used for HPLC or LC-MS/MS analysis after concentrating with nitrogen gas.

The basis of the IAC measurement is the antigen-antibody interaction. All four main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.