This MaxSignal Aflatoxin M1 Immunoaffinity Column can selectively extract Aflatoxin M1 from the sample solution, thereby purifying the sample. The purified sample solution can be directly used for HPLC or LC-MSMS analysis after being blown dried using nitrogen gas and re-dissolved in suitable solvent.

Aflatoxins are toxic secondary-metabolites of a class of fungi (such as Aspergillus flavus and Aspergillus parasiticus). They are highly carcinogenic and are found mainly in grains, peanuts, nuts, cottonseeds, animal feed, vegetable oils, as well as animal tissues and blood. Among them, Aflatoxin B1 ranks first in terms of toxicity, carcinogenicity and frequency of contamination. Aflatoxin M1 is the hydroxylated metabolite of Aflatoxin B1 and a strong carcinogen. Cow’s milk and its products are prone to Aflatoxin M1 contamination.

The basis of the IAC measurement is the antigen-antibody interaction. The antibody is embedded in the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxoids bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Aflatoxin B1 Immunoaffinity Column can selectively extract Aflatoxin B1 from the sample solution, thereby purifying the sample. The purified sample solution can be directly used for HPLC or LC-MSMS analysis after being blown dried using nitrogen gas and re-dissolved in suitable solvent.

Aflatoxins are toxic secondary-metabolites of a class of fungi (such as Aspergillus flavus and Aspergillus parasiticus). They are highly carcinogenic and are found mainly in grains, peanuts, nuts, cottonseeds, animal feed, vegetable oils, as well as animal tissues and blood. Among them, Aflatoxin B1 ranks first in terms of toxicity, carcinogenicity and frequency of contamination.

The basis of the IAC measurement is the antigen-antibody interaction. The antibody is embedded in the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxoids bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Deoxynivalenol Immunoaffinity Column can selectively extract Deoxynivalenol (Vomitoxin, DON) from the sample solution, thereby purifying the sample. The purified sample solution can be directly used for HPLC or LC-MS/MS analysis after concentrating with nitrogen gas and re-dissolved in suitable solvent.

Deoxynivalenol belongs to the trichothecene family and is produced by some Fusarium species. Vomitoxins are mostly distributed in grain seeds such as wheat, barley, and corn, and its content is usually in the range of mg/kg. Due to their high cytotoxicity and immunosuppressive properties, they pose a health threat to both humans and animals.

The basis of the IAC measurement is the antigen-antibody interaction. The antibody is embedded in the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxoids bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Total Deoxynivalenol Immunoaffinity Column can extract Deoxynivalenol (Vomitoxin, DON), as well as its two prominent acetylated derivatives, 3-acetyldeoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), which has a highly targeted purification effect. The purified sample solution can be directly used for HPLC or LC-MS/MS analysis after concentrating with nitrogen gas.

DON belongs to the single-endomycin family of molds and is produced by certain Fusarium fungi. 3-ADON and 15-ADON are derivatives of DON. These toxins are mostly distributed in grain seeds such as wheat, barley, and corn. Due to their high cytotoxicities and immunosuppressive properties, they pose a health threat to humans and animals.

The basis of the IAC measurement is the antigen-antibody interaction. All main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Fumonisin Immunoaffinity Column can selectively extract Fumonisins (B1, B2, B3) from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after concentrating with nitrogen gas and resuspended.

Fumonisin is a metabolite produced by Fusarium fungi. It has acute and chronic toxicities, and is species-specific and organ-specific. Studies have found that high concentrations of fumonisin can cause acute species-specific toxicity symptoms in many domestic and laboratory animals, such as equine leukoencephalomalacia, porcine pulmonary edema, and liver and kidney diseases in sheep. The toxin has also been found to be related to esophageal and liver cancer in humans.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Fumonisin Immunoaffinity Column can selectively extract Ochratoxin A from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Ochratoxin A is a toxic metabolite produced by some species of Aspergillus and Penicillium; it is a mycotoxin with high kidney and liver toxicities, and has teratogenic, mutagenic, and carcinogenic effects.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal T-2/HT-2 Toxin Immunoaffinity Column can selectively extract T-2 and HT-2 Toxins from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

T-2 toxin (T-2) is a mycotoxin produced by a variety of Fusaria. It mainly pollutes food crops such as wheat, barley, and corn, and their products, and is relatively harmful to human health and cattle industry. HT-2 toxin is the main metabolite of T-2 toxin. These two toxins are strong inhibitors of protein synthesis in the body and mainly affect the functions of blood, liver, kidney, pancreatic muscle and lymphocytes. The general clinical symptoms after poisoning are anorexia, vomiting, diarrhea, growth arrest, as well as reproduction and neurological dysfunction, etc.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.

This MaxSignal Total Aflatoxin Immunoaffinity Column can extract Aflatoxins (B1, B2, G1, G2, M1, M2) from the sample solution, thereby having a highly targeted purification effect on the sample. The sample solution that has been purified by passing through the column can be directly used for HPLC or LC-MS/MS analysis after being concentrated with nitrogen gas and resuspended.

Aflatoxins are toxic metabolites of a class of fungi (such as Aspergillus flavus and Aspergillus parasiticus). They are highly carcinogenic and are found mainly in grains, peanuts, nuts, cottonseeds, animal feed, vegetable oils, as well as animal tissues and blood. Among them, Aflatoxin B1 ranks first in terms of toxicity, carcinogenicity and frequency of contamination. Aflatoxin M1 is a hydroxylated metabolite of Aflatoxin B1 and a strong carcinogen. Cow milk and its products are prone to Aflatoxin M1 contamination.

The basis of the IAC measurement is the antigen-antibody interaction. All the main toxin antibodies are embedded throughout the column. After a sample is extracted and filtered, it is slowly passed through the IAC. The toxins bind to their corresponding antibody in the column. The IAC is then washed to remove unbound substances. The toxins are then eluted with the eluent, concentrated using nitrogen gas, then injected into an analytical instrument for detection. Affinity columns can be used in combination with HPLC and LC-MSMS to achieve rapid testing, and to increase signal-to-noise ratio and improve the accuracy of the detection method.

This kit is manufactured to the international quality standard ISO 9001.